Manufacturer of fermenter, bioreactor, Agitator, Reactor, Vessel, Rotary Shaker, BOD Incubator, Ribbon Blender, Vertical Autocalve, Process instruments and fittings

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500 Litter Fermenter Advance

Original price was: ₹800,000.00.Current price is: ₹769,787.00.

500 Litter Fermenter Specification

500L Advance Fermenter – Product Specification

The 500L Advance Fermenter is a high-capacity, semi-automated bioreactor designed for industrial fermentation, biofertilizer production, and enzyme manufacturing. It offers a strong balance between automation, performance, and cost, making it ideal for businesses scaling from pilot to commercial production.

This model integrates PLC-based control, real-time monitoring, and reliable process systems, ensuring consistent product quality and operational efficiency.


Key Features Overview

  • PLC-based control system for stable operation
  • Continuous online pH monitoring with semi-automatic control
  • Optional DO (Dissolved Oxygen) sensor integration
  • Efficient agitation and aeration system
  • Semi-automatic sterilization and cooling
  • Skid-mounted design for easy installation

Probe & Monitoring System

The 500L Advance Fermenter is equipped with essential sensors:

  • Temperature Sensor (Pt-100)
    • High-precision temperature measurement
    • Maintains optimal fermentation conditions
  • Online pH Measurement
    • Real-time pH monitoring
    • Integrated with semi-automatic dosing system
  • DO Sensor (Optional – On Demand)
    • Can be added based on process requirement
    • Improves oxygen transfer efficiency
  • Skid Mounted System
    • Pre-assembled unit for faster installation
    • Ensures system stability

Control System & Automation

Designed for reliable and efficient process control:

  • Controlling Processor:
    • Industrial-grade PLC system
    • Provides stable and repeatable operation
  • Temperature Control:
    • Semi-automatic with 5 solenoid valves and pump integration
    • Ensures accurate heating and cooling
  • Agitation Control:
    • Controlled agitation system
    • Maintains uniform mixing and nutrient distribution

Process Control Capabilities

The system supports semi-automated fermentation operations:

  • Media Sterilization:
    • Semi-automatic sterilization process
    • Reduces contamination risk
  • Process Cooling:
    • Semi-automatic cooling system
    • Maintains stable operating temperature
  • Aeration Control by Rotameter:
    • Manual airflow adjustment with visual indication
    • Ensures proper oxygen supply
  • pH Control:
    • Semi-automatic pH regulation
    • Requires minimal operator intervention
  • Pressure Control:
    • Integrated pressure monitoring system

Pump & Fluid Handling

  • Fixed Speed Peristaltic Pump
    • Available on demand
    • Suitable for dosing acids, bases, and nutrients
    • Quantity customizable as per process needs

Piping & Installation

  • Piping System:
    • Flexible Plug & Play piping from skid to fermenter
    • Easy installation and maintenance
  • Installation Scope:
    • Buyer scope
    • Optional onsite support available

Technical Specification Table

Parameter 500L Advance Fermenter Specification
Vessel Capacity 500 Liters
Control System PLC Based
Temperature Sensor Pt-100 (Included)
pH Measurement Online (Semi-Automatic Control)
DO Sensor On Demand
Agitation System Controlled
Media Sterilization Semi-Automatic
Cooling System Semi-Automatic
Aeration Control Rotameter Based
Pressure Control Available
Pump System On Demand
Piping Flexible Plug & Play
Installation Buyer Scope
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500 Litter Fermenter Advance

500L Advance Fermenter – Product Specification

The 500L Advance Fermenter is a high-capacity, semi-automated bioreactor designed for industrial fermentation, biofertilizer production, and enzyme manufacturing. It offers a strong balance between automation, performance, and cost, making it ideal for businesses scaling from pilot to commercial production.

This model integrates PLC-based control, real-time monitoring, and reliable process systems, ensuring consistent product quality and operational efficiency.


Key Features Overview

  • PLC-based control system for stable operation
  • Continuous online pH monitoring with semi-automatic control
  • Optional DO (Dissolved Oxygen) sensor integration
  • Efficient agitation and aeration system
  • Semi-automatic sterilization and cooling
  • Skid-mounted design for easy installation

Probe & Monitoring System

The 500L Advance Fermenter is equipped with essential sensors:

  • Temperature Sensor (Pt-100)
    • High-precision temperature measurement
    • Maintains optimal fermentation conditions
  • Online pH Measurement
    • Real-time pH monitoring
    • Integrated with semi-automatic dosing system
  • DO Sensor (Optional – On Demand)
    • Can be added based on process requirement
    • Improves oxygen transfer efficiency
  • Skid Mounted System
    • Pre-assembled unit for faster installation
    • Ensures system stability

Control System & Automation

Designed for reliable and efficient process control:

  • Controlling Processor:
    • Industrial-grade PLC system
    • Provides stable and repeatable operation
  • Temperature Control:
    • Semi-automatic with 5 solenoid valves and pump integration
    • Ensures accurate heating and cooling
  • Agitation Control:
    • Controlled agitation system
    • Maintains uniform mixing and nutrient distribution

Process Control Capabilities

The system supports semi-automated fermentation operations:

  • Media Sterilization:
    • Semi-automatic sterilization process
    • Reduces contamination risk
  • Process Cooling:
    • Semi-automatic cooling system
    • Maintains stable operating temperature
  • Aeration Control by Rotameter:
    • Manual airflow adjustment with visual indication
    • Ensures proper oxygen supply
  • pH Control:
    • Semi-automatic pH regulation
    • Requires minimal operator intervention
  • Pressure Control:
    • Integrated pressure monitoring system

Pump & Fluid Handling

  • Fixed Speed Peristaltic Pump
    • Available on demand
    • Suitable for dosing acids, bases, and nutrients
    • Quantity customizable as per process needs

Piping & Installation

  • Piping System:
    • Flexible Plug & Play piping from skid to fermenter
    • Easy installation and maintenance
  • Installation Scope:
    • Buyer scope
    • Optional onsite support available

Technical Specification Table

Parameter 500L Advance Fermenter Specification
Vessel Capacity 500 Liters
Control System PLC Based
Temperature Sensor Pt-100 (Included)
pH Measurement Online (Semi-Automatic Control)
DO Sensor On Demand
Agitation System Controlled
Media Sterilization Semi-Automatic
Cooling System Semi-Automatic
Aeration Control Rotameter Based
Pressure Control Available
Pump System On Demand
Piping Flexible Plug & Play
Installation Buyer Scope
Gemini said 500 Liter Advanced Fermenter: The Ultimate Bioprocessing Solution

The 500 Liter Advanced Fermenter represents a significant leap in bioprocessing technology, designed to meet the rigorous demands of industrial-scale microbial cultivation. This system is engineered for precision, scalability, and durability, making it an essential asset for pharmaceutical, nutraceutical, and enzyme manufacturing sectors. With integrated automation and high-grade stainless steel construction, it ensures sterile environments and optimal yield.

Advanced Features of the 500L Fermentation System

Our advanced model features a high-performance agitation system, precise pH and Dissolved Oxygen (DO) control, and a sophisticated Temperature Control Unit (TCU). The vessel is polished to a mirror finish (Ra < 0.4 µm) to prevent microbial attachment and ensure ease of sterilization. Whether you are scaling up from a pilot plant or optimizing an existing production line, this equipment provides the stability and data logging capabilities required for modern regulatory compliance.

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Supporting the industrial growth of East India, we operate as a Fermenter Manufacturer in Durg. Our advanced fermenters are built with SS 316L contact parts, ensuring zero corrosion and long-term reliability in harsh environments.

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In the heart of Tamil Nadu’s agricultural belt, being a Fermenter Manufacturer in Erode allows us to supply systems for organic pesticide and bio-stimulant production. Our 500L units are ideal for medium-scale industrial applications.

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Frequently Asked Questions (FAQs)

1. What is the material of construction for the 500L Advanced Fermenter?
The 500L Advanced Fermenter by Uma Pharmatech Machinery is constructed using high-grade SS 316L for all contact parts and SS 304 for non-contact parts to ensure maximum sterility.

2. Can this fermenter be used for both aerobic and anaerobic processes?
Yes, Uma Pharmatech Machinery designs the 500L advanced system with versatile sparger and gas-mixing options, making it suitable for both aerobic and anaerobic fermentation.

3. Does the system support Sterilization-In-Place (SIP)?
Absolutely. The 500L Advanced Fermenter from Uma Pharmatech Machinery is fully SIP-capable, allowing for automatic steam sterilization of the vessel and piping without disassembly.

4. What kind of automation is provided with the equipment?
Uma Pharmatech Machinery provides PLC-based automation with a user-friendly HMI touch screen, enabling precise control over pH, temperature, DO, and agitation speeds.

5. Is the agitation system customizable?
Yes, Uma Pharmatech Machinery offers various impeller designs (Rushton, Pitched Blade, etc.) to match the specific shear sensitivity and oxygen transfer requirements of your culture.

6. How does the system handle foaming during fermentation?
The advanced vessels from Uma Pharmatech Machinery include integrated foam sensors and automated anti-foam dosing pumps to manage and suppress foam levels in real-time.

7. What are the cooling and heating options available?
Uma Pharmatech Machinery equips the 500L fermenter with a dimpled or limpet jacketed system, connected to a dedicated TCU for rapid and accurate temperature regulation.

8. Can I monitor the process remotely?
Yes, the advanced automation packages from Uma Pharmatech Machinery support SCADA integration and remote monitoring via secure Ethernet or Wi-Fi connections.

9. Does the fermenter come with validation documentation?
Uma Pharmatech Machinery provides comprehensive DQ, IQ, and OQ documentation to assist our clients in meeting stringent regulatory and GMP requirements.

10. What is the typical lead time for a 500L Advanced Fermenter?
While it depends on customization requirements, Uma Pharmatech Machinery typically delivers these advanced systems within 10 to 14 weeks, including rigorous factory acceptance testing (FAT).

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