Manufacturer of fermenter, bioreactor, Agitator, Reactor, Vessel, Rotary Shaker, BOD Incubator, Ribbon Blender, Vertical Autocalve, Process instruments and fittings

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Advance fermenter 500Litter

Original price was: ₹1,200,000.00.Current price is: ₹1,190,000.00.

Specification of Fermenter-500L

 

Fermenter Vessel Details
Total Volume(Litter) 500L
Diameter(mm) 650
Straight Height(mm) 1500
shell(cylindrical) 5 mm thk ss 316
Jacket 5 mm thk SS 304
Top Body Flange With Dish End
Bottom Dished end( 10% tori spherical)
leg MS
Baffle Recommendation(Off Wall) 4 Nos @ 90 Degree
manhole No
Top Glass 70mm(Vision 30mm)
Inner Finish Mirror Finish
Outer finish Matt Finish
Total Height to be confirmed
Design Criteria
Viscosity 100 cP SG 1.1
Pressure FV to 3kg/cm2 Temp 130 deg C
Mechanical Detail
Sealing Mechanical Seal( Sealmech)
Gearbox (Elmech) Worm Gearbox
Motor HP (Crompton/ BBL/ Havels/ Hindustan) 3 NFLP, 4 Pole, Flanged, 3 Ph, 415 V, 50 Hz,

 

 

 

Impeller Type (From bottom) Ruston Turbine Ruston Turbine Ruston Turbine
Impeller Blade 6 Blade 6 Blade 6 Blade
Agitator Details
MOC Contact Parts SS 316 Shaft Diameter 50 mm
MOC Non-CP MS/CS Shaft Speed(RPM) 187
Air Flow Control Rotameter  (500 LPM)
Scope of Supply Design, manufactur, supply of UPM make agitator assembly. Which includes impeller blades with hub, shaft, lantern assembly with bearing housing  etc.
Scope of Buyer Installation in scope of buyer (Electricity, Insulation, Water, Drain Line, Valves and Fittings and Clamp )

 

 

 

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Advance fermenter 500Litter

 

Description Advance
Probe
Temperature Sensor(Pt-100) Yes
online ph measurement Yes
DO Sensor With 3 Meter Cable and indicator on Demand
skid Yes
Control
Controlling Processor PLC Based
Temperature Control Semi Auto(5 sv With Pump)
Inbuilt Heater in Vessel(Suitable For Biofertilizer Production) on Demand
Agitation Control Yes
Media Sterilization Semi Auto
Process Cooling  Temperature Control Semi Auto
Aeration Control By Rotameter Yes
Ph Control Semi Automatic
Pressure Control yes
Fixed Speed Peristaltic Pump On Demand (Specify Qty)
Piping Flexible (Plug and Play)From Skid To Fermenter) Buyer Scope
Installation Buyer Scope

500L Advance Fermenter – Product Specification

The 500L Advance Fermenter is a high-capacity, semi-automated bioreactor system designed for industrial fermentation, biofertilizer production, and enzyme manufacturing. It offers the perfect balance between automation, performance, and cost-effectiveness, making it an ideal choice for businesses scaling their production.

With a PLC-based control system and essential process automation, this fermenter ensures consistent product quality, improved efficiency, and reliable operation.


Key Features Overview

  • PLC-based control system for stable and accurate operation
  • Continuous online pH monitoring with semi-automatic control
  • Optional DO (Dissolved Oxygen) sensor integration
  • Efficient agitation and aeration system
  • Semi-automatic sterilization and cooling
  • Skid-mounted system for easy installation

Probe & Monitoring System

The 500L Advance Fermenter is equipped with essential monitoring instruments:

  • Temperature Sensor (Pt-100)
    • High-precision temperature measurement
    • Maintains optimal fermentation conditions
  • Online pH Measurement
    • Real-time monitoring of pH levels
    • Integrated with semi-automatic dosing system
  • DO Sensor (Optional – On Demand)
    • Can be added based on process requirements
    • Improves oxygen transfer efficiency
  • Skid Mounted System
    • Pre-assembled unit for quick and easy installation
    • Enhances operational stability

Control System & Automation

Designed to deliver reliable and efficient process control:

  • Controlling Processor:
    • Industrial-grade PLC system
    • Ensures consistent and repeatable operation
  • Temperature Control:
    • Semi-automatic with 5 solenoid valves and pump integration
    • Provides accurate heating and cooling control
  • Agitation Control:
    • Controlled agitation system
    • Ensures uniform mixing and nutrient distribution

Process Control Capabilities

The system supports semi-automated fermentation operations:

  • Media Sterilization:
    • Semi-automatic sterilization cycle
    • Reduces contamination risks
  • Process Cooling:
    • Semi-automatic cooling system
    • Maintains stable operating temperature
  • Aeration Control by Rotameter:
    • Manual airflow adjustment with visual indication
    • Ensures proper oxygen supply
  • pH Control:
    • Semi-automatic pH regulation
    • Requires minimal operator intervention
  • Pressure Control:
    • Integrated pressure monitoring system

Pump & Fluid Handling

  • Fixed Speed Peristaltic Pump
    • Available on demand
    • Suitable for dosing acids, bases, and nutrients
    • Customizable quantity as per process requirement

Piping & Installation

  • Piping System:
    • Flexible Plug & Play piping from skid to fermenter
    • Simplifies installation and maintenance
  • Installation Scope:
    • Buyer scope
    • Optional onsite support available

Technical Specification Table

Parameter 500L Advance Fermenter Specification
Vessel Capacity 500 Liters
Control System PLC Based
Temperature Sensor Pt-100 (Included)
pH Measurement Online (Semi-Automatic Control)
DO Sensor On Demand
Agitation System Controlled
Media Sterilization Semi-Automatic
Cooling System Semi-Automatic
Aeration Control Rotameter Based
Pressure Control Available
Pump System On Demand
Piping Flexible Plug & Play
Installation Buyer Scope

Applications

The 500L Advance Fermenter is widely used in:

  • Biofertilizer production (commercial scale)
  • Enzyme production (Amylase, Protease, etc.)
  • Industrial microbial fermentation
  • Agricultural biotechnology
  • Medium to large-scale production units

Advantages of 500L Advance Fermenter

  • Balanced Automation → Better control at optimized cost
  • Reliable PLC System → Stable and consistent performance
  • Flexible Configuration → Optional DO and dosing systems
  • High Production Capacity → Suitable for commercial operations
  • Upgradeable Design → Can be upgraded to Pro model

Why Choose 500L Advance Fermenter?

The 500L Advance Fermenter is an excellent solution for businesses aiming to increase production capacity with controlled fermentation parameters while maintaining cost efficiency. It offers a strong combination of performance, flexibility, and scalability, making it ideal for industrial applications.

other information

Gemini said
The Future of Bioprocessing: Advanced 500L Fermenter Systems
The biotechnology landscape is rapidly evolving, shifting from simple cultivation to highly controlled, automated bioprocessing. At the heart of this transformation is the Advanced 500L Fermenter System. This specific capacity is the quintessential bridge between pilot-scale development and full commercial manufacturing. Engineered for precision, the advanced 500L system integrates cutting-edge sensors, automated control loops, and superior mechanical design to ensure maximum microbial yield and product purity.

Engineering Sophistication in Modern Fermentation
Unlike basic models, an "Advanced" system focuses on data-driven results. These units are built with high-grade SS316L stainless steel, featuring electro-polished internal surfaces to a finish of less than 0.4 Ra. This level of smoothness is essential for preventing biofilm formation and ensuring the success of Sterilization-In-Place (SIP) cycles.

For enterprises looking to establish high-tech facilities in the southern industrial corridor, finding a reliable Fermenter Manufacturer in Tamilnadu is the first step toward securing international-standard equipment. Whether you are in a major industrial hub or an emerging tech city, the access to localized engineering expertise has never been greater.

Key Features of the 500L Advanced System
The hallmark of an advanced fermenter lies in its automation. These systems typically feature:

Advanced Sensory Integration: Real-time monitoring of pH, Dissolved Oxygen (DO), temperature, foam, and even biomass concentration using optical density sensors.

Mass Flow Controllers (MFCs): Precise gas mixing (Air, O
2

, N
2

, CO
2

) to maintain optimal aerobic or anaerobic conditions.

SCADA-Compatible Control: PLC-based systems that allow for remote monitoring, data logging, and batch reporting, ensuring compliance with global regulatory standards like 21 CFR Part 11.

Industries located in textile and engineering zones often benefit from local specialized fabrication. For example, a Fermenter Manufacturer in Coimbatore or Erode can offer specialized agitation designs that cater to the unique viscosity of bio-polymers or enzyme broths.

Regional Industrial Impact
The distribution of bioprocessing technology across the region has empowered diverse sectors. In the leather and chemical processing zones, a Fermenter Manufacturer in Ambur, Vaniyambadi, or Ranipet provides essential equipment for the production of tanning enzymes and waste treatment microbes.

In the academic and research-heavy corridors of the state, the demand for sophisticated hardware is met by a Fermenter Manufacturer in Chennai or Kanchipuram. These regions focus heavily on biopharmaceuticals and vaccine production, where the precision of an advanced 500L system is non-negotiable. Similarly, the agricultural heartlands are seeing a shift toward bio-fertilizers, supported by a Fermenter Manufacturer in Tiruchirappalli (Trichy) or Thanjavur.

Versatility Across the Supply Chain
From the coastal industries supported by a Fermenter Manufacturer in Thoothukudi (Tuticorin) or Nagapattinam to the inland manufacturing strengths of a Fermenter Manufacturer in Salem or Karur, the 500L system is proving its versatility. It is large enough to produce significant commercial batches of high-value proteins, yet compact enough to be housed in existing facility footprints.

In specialized climate zones, such as those served by a Fermenter Manufacturer in Ooty (Udhagamandalam), advanced systems are equipped with specialized cooling jackets to maintain precise internal temperatures despite external environmental fluctuations. This level of customization is what separates a standard supplier from a true engineering partner.

FAQS

1. What makes a fermenter "Advanced" compared to a basic model?
An advanced fermenter includes automated gas mixing, SCADA integration, and high-precision sensors (like DO and redox) that allow for automated feedback loops, reducing human error.

2. Is the 500L system suitable for pharmaceutical production?
Yes, when manufactured to GMP standards by a Fermenter Manufacturer in Madurai or Hosur, these systems are ideal for producing vaccines, antibiotics, and therapeutic proteins.

3. What type of agitation is best for the 500L scale?
For microbial work, Rushton turbines are standard. However, for shear-sensitive cells, pitched blade impellers are often recommended.

4. Can I monitor the fermentation process remotely?
Yes, advanced systems feature PLC/SCADA systems that can be accessed via secure networks for real-time monitoring and control.

5. How is sterilization handled in a 500L vessel?
Advanced units utilize automatic Sterilization-In-Place (SIP) using pressurized steam, which ensures the vessel, valves, and piping are completely sterile.

6. Are there manufacturers available in the southern tip of the country?
Yes, you can find a Fermenter Manufacturer in Nagercoil or Tirunelveli capable of providing high-quality bioprocessing solutions.

7. How long does a typical fermentation batch last?
It varies by organism, but most microbial batches last between 24 to 72 hours, while fungal or cell culture batches can last much longer.

8. Can these systems be used for food and beverage production?
Absolutely. A Fermenter Manufacturer in Dindigul or Kumbakonam can customize these vessels for dairy starters, probiotics, or specialized beverage fermentation.

9. What kind of support is available in the industrial western zone?
Enterprises can rely on a Fermenter Manufacturer in Tiruppur or Pollachi for robust mechanical support and localized maintenance services.

10. How do I ensure spare parts availability?
Working with a regional partner, such as a Fermenter Manufacturer in Vellore, Gudiyatham, or Pudukkottai, ensures faster turnaround for gaskets, seals, and sensor calibrations.

conclusion

The 500L Advanced Fermenter is more than just a vessel; it is a sophisticated biological reactor designed for the next generation of industry. Whether you are scaling up in Sivakasi, Rajapalayam, or Neyveli, or seeking the academic rigor of a Fermenter Manufacturer in Karaikudi, investing in advanced automation is the key to unlocking consistent, high-quality biological production.

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